Saying that there are no insulting words is ridiculous. Especially when you say that they always exist in context - that's not true. Words often exist without context or in an unclear context (e.g. graffiti where there is no context, online text where there is limited/unclear context due to lack of prosodic and visual cues etc. - very relevant here). If I type one word randomly in a game, there's no context - if it's an insulting word though, somebody is much more likely to be offended and report me for it than if it were a neutral word.
Whether or not the individual words are "anti-female" was actually the topic here... so yes, it did matter. That's what we were discussing. Any player can be called a 'retard' but, if a player reveals their gender to be female, they're open themselves up to a load of "anti-female" insults which wouldn't have been directed at them if they didn't reveal their gender.
But you're right, gender equality is irrelevant! What a trivial matter! Let's focus on real problems like how to balance Oracle's Elixir or what to build on Jayce!!